Main Pharmacogenomics: Methods and Protocols (Methods in Molecular Biology, 311)
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Pharmacogenomics: Methods and Protocols (Methods in Molecular Biology, 311)

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Expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with HaploChIP, SNP genotyping in DNA pools, and PharmGKB, the pharmacogenetics and pharmacogenomics knowledge base. The methodologies for genotyping include denaturing high-performance liquid chromarography, pyrosequencing, kinetic-fluorescence detection, mass spectrometry, and TaqMan assay for insertion/deletions.
Request Code : ZLIBIO4280715
Categories:
Year:
2005
Publisher:
Humana
Language:
English
Pages:
224
ISBN 10:
1588294404
ISBN 13:
9781588294401
ISBN:
1588294404,9781588294401

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