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Voltage-Gated Ion Channels as Drug Targets (Methods and Principles in Medicinal Chemistry) Edition: 1
Voltage-Gated Ion Channels as Drug Targets (Methods and Principles in Medicinal Chemistry) Edition: 1
David J. Triggle, Murali Gopalakrishnan, David Rampe, Wei Zheng, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
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Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology.After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development.For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.
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